ACTIVITY REPORT活動報告
研究業績
2014年度業績
- Uehara T, Yamasaki T, Okamoto T, Koike T, Kan S, Miyauchi S, Kira J, Tobimatsu S:Efficiency of a “small-world” brain network depends on consciousness level: a resting-state fMRI study. Cerebral Cortex 24:1529-39, 2014.
- Yonekawa T, Murai H, Utsuki S, Matsushita T, Masaki K, Isobe N, Yamasaki, Yoshida M,Kusunoki S, Sakata K, Fujii K, Kira J: A nationwide survey of hypertrophic pachymeningitis in Japan. J Neurol Neurosurg Psychiatry 85: 732-739, 2014.
- Ainiding G, Kawano Y, Sato S, Isobe N, Matsushita T, Yoshimura S, Yonekawa T, Yamasaki R, Murai H, Kira J:Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese. J Neurol Sci 337: 147-150, 2014.
- Cui YW, Kawano Y, Yamasaki R, Shi N, Masaki K, Isobe N, Yonekawa T, Matsushita T, Tateishi T, Hayashi S, Kira J:Decreased CCR2 and CD62L expressions on peripheral blood classical monocytes in amyotrophic lateral sclerosis. Clin Exp Neuroimmunol 5: 92-96, 2014.
- Kira J, Itoyama Y, Kikuchi S, Hao Q, Kurosawa T, Nagato K, Tsumiyama I, von Rosenstiel P, Zhang-Auberson L, Saida T:Fingolimod (FTY720) therapy in Japanese patients with relapsing multiple sclerosis over 12-months: results of a phase 2 observational extension. BMC Neurology 2014: 14: 21. doi: 10.1186/1471-2377-14-21.
- Cui Y, Masaki K, Yamasaki R, Imamura S, Suzuki SO, Hayashi S, Sato S, Nagara Y, Kawamura MF, Kira J:Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model. J Neuroinflam 11: 42-57, 2014.
- Arahata H, Ohyagi Y, Iinuma KM, Tanaka M, Tateishi T, Yamasaki R, Matshushita T, Kira J: Early inhibition of tumor necrosis factor-α and interleukin-6 in muscle tissue as a therapy for dystrophinopathy in mdx mice. Clin Exp Neuroimmunol 5: 371-377, 2014.
- Yoshimura S, Isobe N, Matsushita T, Masaki K, Sato S, Kawano Y, Ochi H, Kira J: Genetic and infectious profiles influence cerebrospinal fluid IgG abnormality in Japanese multiple sclerosis patients. PLos ONE 2014 Apr 15; 9(4): e95367.
- Hagiwara K, Ogata K, Okamoto T, Uehara T, Hironaga N, Shigeto H, Kira J, Tobimatsu S: Age-related changes across the primary and secondary somatosensory areas: an analysis of neuromagnetic oscillatory activities. Clin Neurophysiol 125: 1021-1029, 2014.
- Doi H, Song ZY, Yoshimura S, Tateishi T, Yonekawa T, Yamasaki R, Murai H, Matsushita T, Kira J:Distinct cytokine and T helper cell profiles between patients with multiple sclerosis who had or had not received interferon-beta. Clin Exp Neuroimmunol 5: 321-327, 2014.
- 吉良潤一、大八木保政、谷脇考恭、犬塚貴、吉井文均、青木正志、天野隆弘、豊島至、 福武敏夫、橋本洋一郎:神経内科教育の実態と課題:大学院 臨床神経学 54: 349-358, 2014.
- Shiraishi W, Hayashi S, Kamada T, Isobe N, Yamasaki R, Murai H, Ohyagi Y, Kira J: A case of neuromyelitis optica harboring both anti-aquaporin-4 antibodies and a pathogenic mitochondrial DNA mutation for Leber’s hereditary optic neuropathy. Mult Scler 20: 258-260, 2014.
- 宇根隼人、上原平、立石貴久、重藤寛史、大八木保政、吉良潤一:B型インフルエンザ罹患後に非痙攣性てんかん重積状態を来たした1例.臨床神経54:227-230,2014.
- 秋山拓也、立石貴久、河村信利、松下拓也、吉良潤一:多発性硬化症による症候性三叉神経痛にコデインが著効した一例.日本ペインクリニック学会誌21:54-57, 2014.
- Fujii T, Hayashi S, Kawamura N, Higuchi M, Tsugawa J, Ohyagi Y, Hayashi YK, Nishino I, Kira J: A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of sternocleidomastoid and trapezius muscles. J Neurol Sci 343: 206-210, 2014.
- Kira J: Evidence for efficacy of a drug widely used without authorization in multiple sclerosis: mycophenolate mofetil. J Neurol Neurosurg Psychiaty 85: 246, 2014.
- 山崎亮、吉良潤一:アトピー性脊髄炎.神経症候群II. -その他の神経疾患を含めて-[第2版].日本臨牀 別冊 新領域別症候群シリーズ No.27: 822-826, 2014.
- 上田麻紀、河村信利、吉良潤一:遺伝性腕神経叢神経障害.神経症候群II. -その他の神経疾患を含めて-[第2版].日本臨牀 別冊 新領域別症候群シリーズ No.27: 883-886, 2014.
- 真崎勝久、吉良潤一:多発性硬化症.「神経系」.別冊BIO Clinica慢性炎症と疾患.pp.16-22, 2014.
- 山崎亮、吉良潤一:遺伝性脱髄性疾患.神経症候群IV. -その他の神経疾患を含めて-[第2版].日本臨牀 別冊 新領域別症候群シリーズ No.29: 331-335, 2014.
- 渡邉充、吉良潤一:フィンゴリモド(多発性硬化症治療薬).医学のあゆみ.3000号記念誌249: 434, 2014.
- 林信太郎、吉良潤一:多発性硬化症の痛み.Practice of Pain Management 5: 20-22, 2014.
- Kira J:What we know and do not know about fingolimod: outline and interpretation of results from the Japanese fingolimod core and extension studies. Clin Exp Neuroimmunol 5: 10-18, 2014.
- Kira J:Time to re-visit “Asian modifications” of multiple sclerosis: lessons from the Japanese fingolimod studies. Clin Exp Neuroimmunol 5: 1, 2014.
- 吉良潤一:多発性硬化症の疾患概念、病因、病態.多発性硬化症と視神経脊髄炎.-基礎臨床研究の最新知見-.日本臨牀 72: 1884-1894, 2014.
- 松下拓也、吉良潤一:多発性硬化症のパラダイムシフト―病態から治療まで.その他の疾患修飾薬.Clinical Neuroscience 2014年11月号 中外医学社32: 1291-1295, 2014.
- 米川智、吉良潤一:無菌性髄膜炎・肥厚性硬膜炎とリウマチ性疾患.リウマチ科 52: 482-484, 2014.
- Kira J:Expectations and concerns regarding emerging new disease-modifying drugs for multiple sclerosis: what can we expect in the future?Clin Exp Neuroimmunol 5: 273-274, 2014.
- 吉良潤一:私のKeep Pioneering: 神経科学と免疫科学の統合による神経難病のパラダイムシフトをめざして.臨床神経 54: 939-946,2014.
- 上田麻紀、吉良潤一:Gerstmann症候群.神経症候群XIII. -その他の神経疾患を含めて-[第2版].日本臨牀 別冊 pp. 756-759, 2014.
- 松瀬大、吉良潤一:多発性硬化症・視神経脊髄炎.診療ガイドラインUp-To-Date 2014-2015.門脇孝、宮地良樹、小室一成(監).メディカルレビュー社 pp. 524-529, 2014.
- 米川智、吉良潤一:頭頸部前屈時の疼痛を主訴とした28歳女性. 神経感染症を究める.アクチュアル脳・神経疾患の臨床.辻省次(総編集).水澤英洋(専門編集).中山書店 pp. 311-312, 2014.
- 岩木三保、立石貴久、吉良潤一:第9章 ケアネットワーク.1節 難病医療ネットワークと地域ケアの実際を知る.新ALSケアブック.第二段.日本ALS協会(編). 川島書店 pp. 245-254, 2014.